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PLoS One 7 (8), e42224

When to reach out to your Care Team: If diarrhea lasts more than a day with three or more watery stools If you experience mild to moderate abdominal pain Seek immediate medical care if diarrhea is severe, persistent, or accompanied by dehydration symptoms like dizziness, confusion, or very low urine output

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In this two-tier screening approach, BBB-PAMPA was first employed to eliminate compounds with poor passive permeability, followed by MDR1-MDCK I to screen out P-gp efflux transporters' substrates