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Aldactone is an aldosterone antagonist (blocker) that is approved to treat the following: Heart failure High blood pressure Swelling (ascites) due to liver (hepatic) cirrhosis Swelling due to nephrotic syndrome (a rare kidney condition) Primary hyperaldosteronism (a condition in which your adrenal gland produces too much hormone called aldosterone) It is also used off-label to treat polycystic ovary syndrome (PCOS), excessive hair growth in women (hirsutism), and acne in women

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Ventura-Cots M, Concepcin M, Arranz JA, et al

What they do report is a cascade of positive effects that lead to a more optimized physiological state overall