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Reporting Adverse Events or Safety Concerns If you experience or suspect an adverse event, contamination, or quality issue with this product, report it immediately to: Hospira Pfizer: Manufacturer contact information available on the product vial FDA MedWatch: 1-888-SAFEMED (1-888-723-3633) or online at fda.gov/medwatch Poison Control: 1-800-222-1222 (for toxicology guidance) Your institutional pharmacovigilance system: If you work for a hospital, clinic, or healthcare institution Regulatory Compliance By purchasing and using this product, you agree to comply with all applicable FDA regulations, state pharmacy laws, and professional licensing requirements

J Physiol (Paris) 2001

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Immediately after the game, ice application to the knee for 15-20 minutes addresses acute post-activity inflammation