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"Dual receptor pathway activation via GHRH and GHS receptors produces a synergistic somatotropic release that exceeds the potential of single agonists." Peer-reviewed literature on both components is indexable at PubMed at PubMed Secretagogue Blend Collection and related genomic targets cataloged at the NCBI Genomic Database

In cell studies, Epitalon or Epithalon has been reported to increase telomerase activity and promote telomere elongation, including early human somatic-cell work and a newer 2025 cell-line study