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Heres the context: serious adverse events are rare and typically associated with pre-existing conditions

Different subsets of T cells determine the prognosis of tumors, among which the T cell subsets that are conducive to tumor prognosis and survival mainly include: high levels of CD8 + and CD4 + T cells, high helper T cell (Th)1 to Th2 ratio, and high CD45RO memory T cells (139, 140), while the T cell subsets associated with tumor progression and poor prognosis are predominantly Tregs (141, 142)

Patients who accelerate their own dose increases without medical guidance often experience prolonged or more intense side effects, sometimes lasting 612 weeks or longer