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Protection against ROS is probably due to the protective cytokines and other products by ADSCs, such as IGF, which can prevent oxidation damage on fibroblasts

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The anti-inflammatory effects and observed improvement in psoriasis and HS after GLP-1RA treatment opens the possibility of studying their therapeutic potential in other common inflammatory skin conditions such as bullous pemphigoid, lupus erythematosus, and atopic dermatitis

This dual inhibition is particularly significant given the crosstalk between VEGF and COX-2 pathways