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Although the specific roles of proteases in insecticide resistance remain unclear, insecticide-resistant insects often exhibit elevated intracellular protease activity compared with susceptible insects 33

This ability to visualize a physical entity, even imperfectly, is a significant advance over the previous invisibility of unresolved structures in electron density maps: a fuzzy image of an IDP/IDR is still more informative than having no structural data at all

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