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This makes the formulation particularly beneficial for individuals looking to lose weight while maintaining a toned and defined physique

Moreover, sex-dependent differences in the effects of GLP-1 receptor agonists have been reported clinically, with some evidence suggesting greater weight-loss responses and potentially different pharmacokinetic profiles in women and men (Yang et al., 2025), whereas preclinical studies have shown stronger suppression of alcohol self-administration and reinstatement in males, with females exhibiting less pronounced behavioral effects (Daz-Megido and Thomsen, 2023)

Both groups also received a lifestyle intervention

10.1186/s12951-022-01511-9 37 HoangD