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IGF-1 is a potent survival factor for endothelial cells, stimulating NO production and protecting against oxidative stress-induced apoptosis (126, 127)

[1] Mike points out a potential issue with comparing pure L-citrulline to citrulline malate , since the latter contains less actual citrulline by weight

Los autores del trabajo consideran que este tratamiento debera considerarse en pacientes con diabetes obesos o con sobrepeso, aunque es necesario continuar los estudios para conocer exactamente los efectos de los agonistas de los receptores de GLP-1 en el abordaje de la obesidad en pacientes sin diabetes

This is one of the clinical nuances that tends to surprise patients who come in with a self-diagnosed need for either NAD+ or Sermorelin