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Here, we build on this foundation by determining if the protective effects of CR on the progression and development of AD arise from the restriction of energy alone or as a result of fasting between meals

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Together, our in vitro, in silico, and in vivo data indicate that LDHB and GPX4 work in parallel to suppress lipid peroxidation, particularly in mitochondria, thereby corroborating our hypothesis that LDHB is an important contributor to suppress mitochondria-associated ferroptosis in cancer cells