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This increased level of insulin has two primary consequences for weight - It signals your body to store fat, particularly visceral fat around the abdomen It drives the ovaries to produce more androgens (male hormones), which further disrupt appetite, energy, and metabolism More visceral fat = more insulin resistance = more androgens = more insulin

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Despite their promise, the rapid rise in the use of GLP-1 agonists in a relatively short period of time has led to concern from both scientists and the public regarding the long-term safety and efficacy of these drugs