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Birsoy and colleagues also found how mitochondrial glutathione drives cancer spread: not by acting as an antioxidantan effect ruled out through multiple experimentsbut by signaling to activate ATF4, a transcription factor that helps cancer cells survive in low-oxygen conditions

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doi: 10.1016/j.redox.2018.101084 42 KrystonTBGeorgievABPissisPGeorgakilasAG

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