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This subpopulation of LARS B cells shows a preference for Leu metabolism, which can be induced by a Leu diet to promote mitochondrial NAD + production and oxidative metabolism and recruit NAD + -dependent protein deacetylase SIRTUIN-1 (SIRT1) to participate in the regulation of LARS B cells

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Summary: Vitamin B12 injections after gastric banding are indicated when oral supplementation fails to correct a documented deficiency, neurological symptoms are present, or the patient cannot adhere to daily oral regimens