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The influence of the GM on systemic health through the regulation of immune responses, inflammatory mediators, metabolic pathways, and nervous system function is now widely recognized as substantial and should not be overlooked

Efficacy and safety data were sourced from the STEP trials (Body Mass Index, systolic blood pressure and glycemic status) from a cohort of adults aged on average 48 years with obesity (BMI 30 kg/m2) and 1 obesity-related comorbidities, over a time horizon of 40 years

They're different tools with different risk-benefit profiles