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Description

The SELECT cardiovascular outcomes trial (17,604 patients with preexisting cardiovascular disease, overweight or obesity, without diabetes) demonstrated semaglutide 2.4 mg weekly reduced major adverse cardiovascular events by 20% versus placebo at mean 39.8 months follow-up

Adv Online Pub, Clin Exp Med

They include adding adjunctive therapies that complement GLP-1 activity through different mechanisms

Acute semaglutide treatments were performed on 2 separate days with a 1-day washout period in between, during which PBS was administered before recording