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To study the role of GLP-1R in microglial inflammation, BV-2 cells were preincubated with the selective GLP-1R agonist liraglutide (100 nM, Selleck, TX, USA) and the antagonist exendin(939) (200 nM, MCE, USA) for 24 h, followed by LPS (1 g/ml, SigmaAldrich, MO, USA) stimulation for 24 h

Over the past several weeks, the Central Drugs Standard Control Organisation (CDSCO), in coordination with state Licensing Authorities (SLAs), has conducted a comprehensive nationwide enforcement campaign targeting the illegal distribution, non-compliant dispensing, and misuse of GLP-1-based weight loss medications

Without a gallbladder to store and concentrate bile, fat digestion becomes less efficient, and some patients experience bile reflux gastritis or post-cholecystectomy syndrome with bloating, diarrhea, and constipation

With brand-name drugs available, the FDA has shifted its focus back to safety and regulatory compliance