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Insights into the poor prognosis of allopurinol-induced severe cutaneous adverse reactions: the impact of renal insufficiency, high plasma levels of oxypurinol and granulysin

Ruiz Pons M, Gutirrez Vilar M, Garca Zurita C, Fuentes Ferrer ME

The HMnO 2 nanosystem can decompose surplus H 2 O 2 into O 2 and deplete glutathione (GSH) in the TME, alleviating hypoxia in tumors and efficiently accumulating reactive oxygen species (ROS) [164, 165]

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