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There are no approved therapies for youth that have demonstrated a clinically meaningful impact on body weight or BMI reduction compared with placebo. Hannon said the 2025 American Diabetes Association Standards of Care currently recommend GLP-1 therapy if children and adolescents with type 2 diabetes are unable to achieve an HbA1c of 6.5% or less with metformin or insulin therapy

With emphasis on the stage of incipient diabetic nephropathy

Oxidative stress occurs when you have too many free radicals molecules with an odd number of electrons floating around in your body and not enough antioxidants to neutralize them

As obesity becomes more common globally, the potential patient pool for GLP-1 receptor agonists expands significantly