Severe allergic or skin reaction: rash, blistering or peeling of skin, hives, painful sores in your mouth or around your eyes, fever, trouble breathing, swollen lymph nodes Overactive immune system: fever, rash, belly pain or swelling, brown urine, yellowing of the whites of the eyes or skin Irregular heartbeat Suicidal thoughts and behavior Meningitis (brain inflammation): stiff neck, rash, fever, light sensitivity, headache, chills, nausea, vomiting Effects of other drugs, drug classes and over-the-counter products on Lamictal XR The following medications may interact with Lamictal XR: Valproate increases lamotrigine concentrations more than 2-fold Carbamazepine, phenytoin, phenobarbital, primidone, and rifampin decrease lamotrigine concentrations by approximately 40% Estrogen-containing oral contraceptives decrease lamotrigine concentrations by approximately 50%
For now, the metabolic profile (blood pressure, lipids, weight loss) is strongly favorable
The escalation schedule is not arbitrary
Microdosing allows for: Lower overall medication exposure
