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In a study, it was found that the MDA level increased in epilepsy patients compared to the healthy control group 21

8), that was consistent with its established neurotoxic effects in rodent models 55,56 .This cytokine dysregulation suggests a mechanistic link between MSG-induced neuroinflammation and cognitive deficits, and emphasize the critical role of neuroinflammatory cascades in mediating excitotoxicity-induced neurodegeneration 101,102

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Isolation and culture of lung fibroblasts Lung tissue of former smokers (defined as quitting smoking for at least one year before surgery) with normal lung function or GOLD stage IV COPD was obtained from patients undergoing surgery for resection for pulmonary carcinoma or lung transplantation