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GH-axis biology: because CJC-1295 increases GH/IGF-1 signaling, fluid retention, edema, joint discomfort, paresthesias, carpal-tunnel-like symptoms, and glucose-handling changes are relevant theoretical or downstream safety endpoints

Interleukin-8 is related to poor chemotherapeutic response and tumourigenicity in hepatocellular carcinoma

However, further in vivo experiments and toxicity assessments of normal hematopoietic stem cells are needed to determine their clinical translational value