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The endothelial cell-based in-vitro model of the BBB was also found to experience an increase in ROS after exposure to ART combination, and the resulting cytotoxicity was attributed to mitochondrial and oxidative stress mechanisms since mitochondrial potential and ATP levels were altered as well as the levels of glutathione and malondialdehyde (Manda et al

Un antioxydant, prsent en excs massif ou sans ses cofacteurs, peut paradoxalement favoriser loxydation au lieu de la combattre

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