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Metformin, a medication for individuals with type 2 diabetes mellitus, was found to decrease vitamin B 12 absorption possibly by tying up free calcium required for absorption of the IF-B 12 complex (143)

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Jeon YJ, Khelifa S, Ratnikov B, Scott DA, Feng Y, Parisi F, Ruller C, Lau E, Kim H, Brill LM, Jiang T, Rimm DL, Cardiff RD, Mills GB, Smith JW, Osterman AL, Kluger Y, Ronai ZA (2015) Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies

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