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Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are endogenous incretins that regulate weight through their receptors (R)

Semaglutide GLP-1 can help patients achieve a level of weight loss previously unattainable outside of invasive surgery

The pill may appeal to people who are averse to needles, have dexterity limitations that make self-injecting challenging, or who travel or dont have easy access to refrigeration, which the injectables require

The drugs have shown positive effects on liver function tests and possible advantages in non-alcoholic fatty liver disease (Liao et al