Modes of action against cancer cells including: inducing apoptosis by cytochrome c release, direct cell membrane lysis (necrosis), inhibiting angiogenesis, inducing autophagy-mediated cell death and immune cell regulation
BMC Musculoskelet Disord 25 , 700 (2024)
L. I. Fedoreyeva, I. I. Kireev, V. Kh. Khavinson, and B. F. Vanyushin, Penetration of short fluorescence-labeled peptides into the nucleus in HeLa cells and in vitro specific interaction of the peptides with deoxyribooligonucleotides and DNA, Pleiades Publishing Ltd, Nov. 2011. doi: 10.1134/s0006297911110022
It does not show that cagrilintide is approved, prescribable, or safe long-term it remains investigational, and a pending regulatory submission is not an approval