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Ether lipids promote susceptibility to ferroptosis, particularly when containing a polyunsaturated fatty acyl (PUFA) chain 51,52

106: 10781091, doi: Anthony JC, Anthony TG, Kimball SR, Jefferson LS

For researchers investigating the metabolic basis of obesity and the role of NAD+ metabolism in fat accumulation, 5-Amino-1MQ provides a selective tool for understanding NNMT's contribution to metabolic dysfunction

Notably, despite mechanistic differences, our combination therapys efficacy in mitigating cognitive deficits and reducing A pathology in APP/PS1 mice was comparable to Donepezils