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HGF activates c-MET receptor in a paracrine manner by exerting its pleotropic effects through controlling several transmission cascades such as the mitogen-activated protein kinase (MAPK), phosphatidylinositol-3 kinase (PI3K)/AKT, and Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathways [7]

In rats with short bowel syndrome from intestinal resection, BPC-157 was given orally or by injection for one month

Research Applications (Observational Data from Published Studies) The following points summarize observations reported in scientific literature from preclinical (mostly rodent/rabbit) and early-phase human studies and are provided solely for informational and research-planning purposes

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