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In addition, the mean corpuscular volume (MCV), which is responsible for measuring the size of red blood cells, would be increased to a level greater than 100

It significantly reduced the expression of APP and p-tau in the hippocampus of AD mice and improved spatial learning and memory abilities

The stress of midlife (and menopause!) is a factor as well

Preclinical Onset Data (Animal Models Not a Human Timeline) The cleanest independent support for Dihexa is a 2021 study from a Chinese group (Sun et al., Brain Sciences, PMID 34827486) in APP/PS1 Alzheimer's-model mice