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However, DPP-4is are still commonly prescribed in patients with T2D and atherosclerotic cardiovascular disease (ASCVD)

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This was further supported by another study comparing GLP-1R agonists to thiazolidinedione and long-acting insulin where GLP-1R agonists did not increase the risk of diabetic retinopathy over an average treatment time of less than 1 year (Wang et al., 2018)

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The IC metric quantifies observed-to-expected reporting discrepancies through the Bayesian Confidence Propagation Neural Network framework (BCPNN) 29 , while EBGM estimates posterior reporting rates by integrating prior reporting patterns and adjusting for cross-drug variability 27,30

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D., & Amyx, B

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