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Patient voice, quality-of-life measures, and patient-reported outcomes are gaining importance alongside traditional clinical endpoints, reflecting a broader shift toward value-based healthcare

Geriatric Vitamin B12 deficiency is common among elderly patients, affecting around 20% of some communities

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These include eczema, dermatitis (contact, atopic, seborrheic, nummular), tinea, lichen planus, lichen simplex, pityriasis rosea, cutaneous lupus erythematosus, syphilis, drug reactions, squamous cell carcinoma in situ, and mycosis fungoides (cutaneous T-cell lymphoma) (Armstrong 2014