If you want to assess your own metabolic baseline before any protocol, the key markers are: fasting insulin and fasting glucose (calculate HOMA-IR: glucose multiplied by insulin divided by 405, target below 2), high-sensitivity CRP (below 1), ferritin (50 to 100), free T3, and the triglyceride-to-HDL ratio (below 2)
Compared with those who didn't take GLP-1s, those who did had a reduction of 10% to 20% in heart failure, cardiac arrest, lung failure, and pneumonia, and Alzheimer's disease and other types of dementia
Risk of symptomatic gallstones and cholecystectomy after a very-low-calorie diet or low-calorie diet in a commercial weight loss program: 1-Year matched cohort study
But for the millions of patients in high-prescription states who are already suffering symptoms without understanding why, the tipping point may have arrived too late