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Cardiac outcomes with pregnancy after cardiotoxic cancer therapy in childhood
It is mostly an acquired condition, which is most frequently caused by Graves disease, toxic multinodular goiter or toxic adenoma ( Hyperthyroidism is associated with unbalanced immune responses, including abnormal antibody production (either increased or decreased) (43), increased migration of polymorphonuclear leukocytes (44), increased lymphocyte proliferation (45) and increased macrophages reactive oxygen species (ROS) production (46)
This reduces overall efficacy and makes progress assessment impossible
1986 Jun;24(6):693-8
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