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Clinical trial results concerning pancreas-related adverse effects have also been added The postmarketing experience section now includes reports of alopecia (hair loss) and dysesthesia (altered sense of touch)

In clinical investigations, Korean PNO reduced caloric consumption in overweight women (Hughes et al., 2008), enhanced the release of satiety hormones, and lowered appetite in post-menopausal overweight women (Pasman et al., 2008)