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[57] Several serious, even life-threatening diseases cause elevated serum haptocorrin, measured as abnormally high serum vitamin B 12 , while at the same time potentially manifesting as a symptomatic vitamin deficiency because of insufficient vitamin bound to transcobalamin II which transfers the vitamin to cells

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The content of trigonelline decreases continuously throughout roasting, while nicotinic acid and N methylpyridinium increases, with N-methylpyridinium being the major thermal product up to the dark medium roast, similar to the Purity Dark Roast

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