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1 In this study, adverse events considered possibly to be caused by hydroxocobalamin were chromaturia (n=5), pink-to-red skin discoloration (n=3), increase in heart rate (n=1), and elevated blood pressure (n=1)

Each sample (1 g) was dissolved in 9 mL of phosphate-buffered saline (PBS, pH 5.5) and subjected to UVVis spectrophotometric analysis to determine uniform distribution of the active constituents

In severe osteoarthritis, the limiting problem is often structural joint degeneration

Nitric oxide relaxes blood vessels, which reduces heart strain and can boost physical performance by getting more oxygen and nutrients to tissues