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Within the N-terminal nine amino acids, oxyntomodulin differs from GLP-1 by 2 residues, with Ala8 and Glu9 of GLP-1 replaced by Ser2 and Gln3 in oxyntomodulin (Fig

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[2] [3] Most are administered via subcutaneous injection either once daily or once weekly, though oral semaglutide (Rybelsus) is taken daily by mouth

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