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The main cause of recurrence after bilateral thyroidectomy is the presence of ectopic hyperplastic thyroidal tissue, which is reported in up to 9% of cats 13

Wakamatsu K, Nakao K, Tanaka H, Kitahori Y, Tanaka Y, Ojika M, Ito S (2019) The oxidative pathway to dopamine-protein conjugates and their pro-oxidant activities: implications for the neurodegeneration of Parkinsons disease

Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation