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Taurine deficiency as a cause of vigabatrin-induced retinal phototoxicity

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In the past ten years, a series of Phase III trials showed that the synthetic GLP-1/GIP agonists are effective in lowering blood sugar in type 2 diabetic subjects who were both treatment-nave or on typical first-line therapies such as metformin and insulin

The GIP receptor activation component of tirzepatide may provide additional effects, as GIP receptors are expressed on immune cells and adipocytes, potentially modulating inflammatory responses in these tissues