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10,11 Curcumin Preclinical and in vitro data suggest that curcumin can inhibit DPP-4 activity and enhance glycemic control in diabetic animal models, potentially prolonging the active life of GLP-1, although this has not been confirmed in human mechanistic studies

DOI: 10.1016/j.cmet.2022.07.013

Safety, Contraindications, and Medical Monitoring GLP-1 medications carry established contraindications: personal or family history of thyroid cancer, medullary thyroid carcinoma (MTC), multiple endocrine neoplasia type 2 (MEN2), pregnancy, pancreatitis risk, and severe kidney disease

One such promising avenue is the use of Nicotinamide Adenine Dinucleotide (NAD+) injections, a treatment gaining attention for its potential anti-aging benefits