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If p -values 0.05, the difference between groups was considered to be statistically significant

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Following the 11 June 2026 MHRA approval, NHS coverage will require a separate assessment by NICE for cost-effectiveness in the NHS setting

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Smaller meals, less heavy fat at once, slower eating

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Finally, while the sample was sufficient to assess sex differences with semaglutide, the limited number of females in cohort 2 precluded meaningful comparisons for tirzepatide and retatrutide

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