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Screening sera of individuals from endemic areas of the state of Minas Gerais, Brazil revealed higher anti-TSP-2 IgG1 and IgG3 antibodies among putatively resistant individuals, though no anti-TSP-1 antibodies were found

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Clinical criteria Acute or subacute cutaneous lupus Chronic cutaneous lupus Oral ulcers Nonscarring alopecia Synovitis involving 2 or more joints Serositis involving lungs or heart Renal involvement Neurological involvement Haemolytic anaemia leukopenia or lymphopenia Thrombocytopenia Immunological criteria Raised ANA level A raised anti-dsDNA antibody level Presence of anti-Sm Positive antiphospholipid antibody (lupus anticoagulant, false positive rapid plasma reagin, high-titre anticardiolipin antibody, positive anti2-glycoprotein I) Low complement levels Positive direct Coombs test * SLICC Systemic Lupus International Collaborating Clinics