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"But microdosing has not been well studied in clinical trials, and most of the data is anecdotal." She said that when someone asks her about microdosing a GLP-1, she advises that, since it's off-label (meaning not approved by the FDA), carefully monitoring their blood sugar, weight, and symptoms is essential

Liraglutide and semaglutide represent human GLP-1(737) analogs, which have specific amino acid changes and fatty-acid side chains to extend their duration of action

Individuals with a history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should avoid GLP-1 receptor agonists

Obesity , 28 (6), 10501061