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Symptome: Vegetativ: Hohes Fieber Tachykardie Tachypnoe Psychiatrisch: Vigilanzminderung (verminderte Wachheit) Stupor Verwirrtheit Mutismus Extrapyramidalmotorisch: Rigor Tremor Akinesie Diagnostik: Erhhte Kreatinkinase (CK) Erhhte Transaminasen Leukozytose Metabolische Azidose Therapie: Antipsychotika absetzen Flssigkeitssubstitution Dopaminagonisten (Bromocriptin) Dantrolen Ultima Ratio: Elektrokonvulsionstherapie (EKT) Differentialdiagnosen: Serotonin-Syndrom Maligne Hyperthermie ( siehe Ansthetika ) Pernizise Katatonie Achtung Bei schwerem Verlauf ist eine intensivmedizinische Betreuung notwendig

Pioglitazone, a diabetes medication, may benefit selected patients with biopsy-proven NASH, but is also specialist-led and off-label , with potential risks including weight gain, fluid retention, heart failure, and increased fracture risk

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