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doi: 10.1093/abt/tbac028 Knox EG, Aburto MR, Clarke G, Cryan JF, ODriscoll CM

"Interventions for melanoma in situ, including lentigo maligna"

After treatment with CPP-CAND, a significant reduction of approximately 7.1-fold in the number of FOXO4 foci was observed in the nuclei of the senescent cells

Thus, combining these two multiplies the action