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The increased levels of L-DOPA dependent ROS was significantly reduced upon Sp exposure, both in wild type and park 13 flies (Fig

This evidence offers a solid theoretical foundation for the future use of catalpol in the settlement of heart diseases (Table 2

It also helps in reversing the imbalance of matrix metalloproteinases (MMP-9) and their inhibitors (TIMP-1), and in preventing epithelial-mesenchymal transition (EMT) through the modulation of Nrf2, NF-B, and TGF-1/Smad2/3 signaling pathways 6

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