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Injecting in the same spot repeatedly can lead to lipohypertrophya buildup of scar tissue and fat that impairs absorption and can create lumps

10.1002/jcp.29391 [DOI] [PubMed] [Google Scholar] Li S., He Y., Chen K., Sun J., Zhang L., He Y., et al

Nevertheless, the direction of effect was consistent: 15 of 18 individual point estimates lay on the increased-risk side of the null, and the pooled result remained statistically significant under both the DerSimonianLaird and restricted maximum-likelihood estimators

your body already makes it), that doesnt mean abusing it is a smart idea