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Similar to previously approved GLP-1RAs, weight loss is a common side effect of Tirzepatide which prompted research focused on its use as a primary weight loss therapy
doi: 10.1016/j.biopha.2025.118731, 15
If side effects remain intolerable, your healthcare provider may recommend staying at a lower dose longer, switching to oral semaglutide, or exploring alternative medications
[12] [13] The medication is indicated for adults with type 2 diabetes as an adjunct to diet and exercise, and for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbid condition
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