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Biosci Biotechnol Biochem 61:19771980
There are multiple mechanisms involved in the development of a hypoxic microenvironment, and even within the same tumor the regions and levels of hypoxia are not always uniform (Graham and Unger, 2018)
Electrolyte supplementation (sodium, potassium, magnesium) helps maintain proper hydration balance, particularly during the first few months when caloric intake drops most sharply
put forward that the abnormal level of soluble UA in body fluid could augment inflammatory effect through resetting epigenetic reprogramming and immunometabolism of innate immune cells, which was termed as trained immunity (5759)
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