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Molecular mechanism of okra and CD By lowering NMDA receptor expression, okra extract and its phytochemicals (quercetin and rutin) maintain neuronal function in cornu ammonis-3 hippocampal neurons and alleviate learning and memory deficits in dexamethasone-induced mice (Tongjaroenbuangam et al., 2011)

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At the same time, itaconate, a metabolite produced during inflammatory macrophage activation, could inhibit ferroptosis by up-regulating Nrf2 (Nuclear Factor erythroid 2-Related Factor 2) levels, thereby alleviating the symptoms of acute lung injury (ALI) and the presence of macrophages in the lung tissue infiltration (He et al., 2022)

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