FDA nonclinical toxicology review (2023-2024) flagged DNA damage in pituitary cells and injection-site necrosis in animal studies, plus immunogenicity and impurity risks from compounded material, alongside GH/IGF-1-axis effects such as fluid retention, joint discomfort, flushing, and headache reported by users
Once an immune response has been evoked, a second vaccination will expose more S on the surface of cells, and again, altering the location of S could conceivably reduce adverse reactions from immune attack on host cells, especially if multiple rounds of vaccination prove to be required to contain future variants of SARS-CoV-2
Finally, for patients on anabolic medications, awareness of the symptoms of hypercalcemia (nausea, fatigue, bone pain, confusion, increased thirst and urination) is worth having, as this is a known risk of parathyroid hormone analogs
The drug-treated (DT) depression patient group included patients who received drug treatment including antidepressants for the treatment of depression, and the non-drug treated (NDT) group included patients who did not receive drug treatment
